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The study included a 26-week treatment period including up to six weeks of dose escalation, followed by a 6-week post-treatment follow-up, extending to week 32

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Alzheimers disease (AD) is a neurodegenerative disorder that is associated with gradual breakdown of the BBB, permitting entry of plasma-derived neurotoxins, inflammatory cells, and microbial pathogens into the CNS

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FDA NDA filed December 2025

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